Continuous Processing Lines for Pharma
A Continuous process is a process where raw materials are continuously fed into a system at the same time as finished product is continuously removed at the end of the process train. The raw materials are processed in very small quantities, compared to batch processes, and in a controlled manner, which allows the operator to have consistent control over the critical process parameters and therefore the critical product quality attributes.
At GEA, we believe that continuous processing improves the quality of pharmaceutical end products: by focusing on quality during the whole product lifecycle, not just “tested in” quality; and by understanding the capability of your processes, managing sources of variability and decreasing any associated risks.
Our solution for continuous drying and particle processing plants is ConsiGma®, a 6 sigma-inspired manufacturing platform, incorporating different technologies to produce oral solid dosage forms in a continuous, cost-efficient way:
- by collecting more information during R&D phase, in a short time with less product
- by excluding risky, time- and product consuming scale-up exercises
- by introducing online measurement and closed loop control targeting real-time release (6 sigma production)
- by incorporating flexible batch size (JIT production), reducing inventory
- by reducing the energy cost per tablet, reducing environmental impact.
Produkte
Zeigt 4 von 7 an
ConsiGma® 1 - R&D Granulation and Drying
The ConsiGma® 1 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
ConsiGma® Conductor
An indispensable part of the ConsiGma portfolio, the Conductor control system architecture ensures smooth operation and communication between the different elements of a pharmaceutical continuous manufacturing line
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
Downloads
GEA Insights
Kytero 10 - grosse Veränderungen beginnen im Kleinen
Mit dem GEA kytero 10 steht Forschenden und Entwicklern in der Biopharma-, Lebensmittel- und New Food-Industrie nun die neueste Generation eines leistungsstarken Beschleunigers zur Seite.
Genuss neu gedacht
Schokolade ganz ohne Kakao? Kaffee, der lokal produziert wird – ganz ohne Bohnen? Was nach Science-Fiction klingt, könnte bald Realität werden. Klimawandel, Preissteigerungen und ethische Bedenken machen auch vor zwei unserer beliebtesten Genussmittel nicht Halt. Forschende setzen deshalb auf neue Produktionsmethoden. Das Ziel: weniger CO2, mehr Lebensmittelsicherheit, voller Geschmack.
Auf dem Speiseplan: nachhaltigere Eier
GEA unterstützt Kunden beim Testen und Skalieren alternativer Eiprodukte und Zutaten, die durch Präzisionsfermentation hergestellt werden.
