ConsiGma®
ConsiGma® R&D Granulation and Drying (GD)
Based on proven continuous twin-screw granulation technology, the ConsiGma® GD 25/80 has been designed for the small-scale development of continuous granulation processes.
The system comprises the same twin-screw granulator as the smallest unit of the ConsiGma® GD or GS lines and a small dryer that’s similar to one of the drying segments. This allows you to develop your products on the same scale with product quantities starting from just a few 100 grams up to a few kilograms. The results are directly transferrable to the smallest ConsiGma® GD or GC line.
The ConsiGma® GD 25/80 is ideal for pharmaceutical companies who wish to develop a continuous granulation process before the fully integrated production line is installed.
Standard Configuration
- One powder feeder
- One liquid addition system
- Twin-screw granulator
- One dryer segment
Available Options
- Brabender or Ktron Feeder
- Standalone GD 25 w/out dryer segment
- Solvent compatible
- Second liquid addition
- Lighthouse Probe® for LOD measurement
- Melt granulation set-up
Main Benefits
- Controlled granulation
- Less API use during R&D
- Fast R&D
- Reduced time-to-market
- No scale-up from GD 25/80 to GD or GC 25/500
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
Downloads
Produits associés
ConsiGma® Tablet Coating (TC) Modules
The ConsiGma® TC modules are based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Granulation and Compression (GC) Lines
Highly integrated solutions for continuous wet granulation, drying and tablet compression, the ConsiGma® GC lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled granulation and improved quality.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
GEA Insights
GEA et Pulmuone rendent hommage à des générations de fabrication artisanale de naengmyeon
Lorsque le producteur de denrées alimentaires à base végétale sud-coréen Pulmuone a mis GEA au défi de moderniser ses nouilles froides traditionnelles, les « naengmyeon », les spécialistes R&D de GEA ont saisi la balle au bond. Ils ont aidé l’entreprise à développer un plat, qui est aujourd’hui une vraie réussite commerciale et dont la production consomme moins d’eau et d’électricité que les méthodes qui existaient auparavant. Le résultat est, par ailleurs, fidèle aux origines traditionnelles de ce plat et aux racines de Pulmuone, qui sont la santé, le bien-être et le développement durable.
Pre2Fuel : Prêt à prendre son envol
Ce processus novateur signé GEA est une avancée de taille dans le prétraitement des biocarburants tels que les huiles végétales hydrotraitées et les carburants d’aviation durables. En éliminant le processus de blanchissement, les fabricants bénéficient d’économies potentielles substantielles : plus de 50 % de coûts d’exploitation en moins et jusqu’à 12 % d’émissions de CO<sub>2</sub> toujours en moins.
