Liquid Dosage
Liposomes
As a drug delivery system, liposomes offer significant therapeutic benefits in terms of active ingredient targeting and controlled release. Hydrophobic moieties can be dissolved into the liposome membrane — a lipid bilayer — and, as such, they can be used to carry both hydrophobic and hydrophilic molecules.
To deliver molecules to sites of action, the liposome binds and fuses with other bilayers, such as a cell membrane, thus delivering its contents. By making liposomes in a drug solution (which would not normally be able to penetrate the membrane), they can be (indiscriminately) delivered through the lipid bilayer into the cell interior.
High-pressure homogenization is an ideal liposome production method, offering excellent results in terms of reduced vesicle diameters. Further, a wide range of different sizes and distributions can be achieved by altering the applied pressure and the number of passes through the homogenizer.
A wide range of products, including liposomes, can be freeze dried to retain their original properties. By adding water or other solvents, they can be reconstituted easily and very quickly to a usable solution. There is no need for cooling during storage, which is both cost-effective and makes handling easier.
GEA specializes in the design and manufacture of freeze dryers for the pharmaceutical and biotech industries and has an in-depth knowledge of lyophilization technology.
製品および技術
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Aseptic valves & components
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
CIP/SIP ソリューション
GEA の革新的な CIP コンセプトは、包括的な最高規格を満たしています。当社のエキスパートは、プロセスのあらゆる時点で、製品の安全性を保証しています。どのアップグレードも、現場の個々の条件および顧客の要件に適合し、顕著な節約を実現します。
Hygienic pumps
GEA Hilge offers a versatile range of centrifugal and positive displacement pumps for a wide variety of sensitive applications in the beverage, food and pharmaceutical industries.
Lyophilizers (Pharma Freeze Dryers)
GEA's thorough understanding of the lyophilization process enables them to supply a comprehensive range of products and services, comprising laboratory equipment, pilot plants for research and small-scale production batches, industrial size pharmaceutical production freeze dryers.
