Liquid Dosage
Antibiotics
Antibiotics, compounds or substances that combat bacterial infections and kill or slow down their growth, comprise one of the most important groups of drugs in the fight against infectious diseases. Representing around 13% of total pharmaceutical consumption, they have the highest market share of any pharmaceutical product.
In liquid-based applications, the pharmaceutical industry extracts antibiotics from fermentation broths. GEA supports this process with special decanters that facilitate the process, offering efficient direct extraction solutions that are also environmentally friendly.
The Extraction Process
Extraction essentially consists of two combined processes: mixing and separating. GEA has developed a patented decanter that combines the two process steps in a single machine to enhance the extraction of active ingredients.
This decanter allows suspensions with a high solids content to be processed, rendering them suitable for direct antibiotic extraction from the culture solution (which often has a high mycelium content). The previously essential filtration step is no longer required, which not only makes the process continuous, it also prevents the loss of valuable material that was frequently associated with filtration.
Advantages of Direct Extraction
Offering increased total yields of up to 98% compared with conventional counter-current extraction, direct extraction is also significantly more cost-effective (no filter aids are needed). The fermentation broth itself is not diluted by filter wash water, which both reduces the solvent requirement and the risk of infection. In addition, the optimized procedure also reduces wastewater pollution and the actual volume of wastewater produced.
The GEA Solution
Driven by new product innovations, high levels of R&D investment and the pharmaceutical industry’s need to ameliorate the issue of antibiotic resistance, the antibiotic market is expected to show continued growth. From R&D-scale and standalone manufacturing equipment to completely integrated process lines that maximize operational reliability, GEA supplies a complete range of equipment and solutions for the industrial-scale production of antibiotics, antibacterials and anti-infectives.
製品および技術
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CIP/SIP ソリューション
GEA の革新的な CIP コンセプトは、包括的な最高規格を満たしています。当社のエキスパートは、プロセスのあらゆる時点で、製品の安全性を保証しています。どのアップグレードも、現場の個々の条件および顧客の要件に適合し、顕著な節約を実現します。
Hygienic pumps
GEA Hilgeでは、飲料、食品、製薬産業における多岐にわたる感度の高い用途に汎用性の高い遠心ポンプおよび容積型ポンプをご用意しております。
Lyophilizers (Pharma Freeze Dryers)
GEA's thorough understanding of the lyophilization process enables them to supply a comprehensive range of products and services, comprising laboratory equipment, pilot plants for research and small-scale production batches, industrial size pharmaceutical production freeze dryers.
R&D Drying Systems
GEA's versatile range of R&D drying & particle processing equipment - for advanced powder processing within food and dairy products, chemicals and pharmaceuticals.
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Making milk production more sustainable for a growing world
The world's population is growing and with it demand for milk. Dairy is an essential component of many global diets. However, its production can be resource-intensive and impact the environment. GEA’s Christian Müller, Senior Director Sustainability Farm Technologies, sheds light on how technological innovations powered by GEA make milk production more efficient and profitable.
