Liquid Dosage
Liposomes
As a drug delivery system, liposomes offer significant therapeutic benefits in terms of active ingredient targeting and controlled release. Hydrophobic moieties can be dissolved into the liposome membrane — a lipid bilayer — and, as such, they can be used to carry both hydrophobic and hydrophilic molecules.
To deliver molecules to sites of action, the liposome binds and fuses with other bilayers, such as a cell membrane, thus delivering its contents. By making liposomes in a drug solution (which would not normally be able to penetrate the membrane), they can be (indiscriminately) delivered through the lipid bilayer into the cell interior.
High-pressure homogenization is an ideal liposome production method, offering excellent results in terms of reduced vesicle diameters. Further, a wide range of different sizes and distributions can be achieved by altering the applied pressure and the number of passes through the homogenizer.
A wide range of products, including liposomes, can be freeze dried to retain their original properties. By adding water or other solvents, they can be reconstituted easily and very quickly to a usable solution. There is no need for cooling during storage, which is both cost-effective and makes handling easier.
GEA specializes in the design and manufacture of freeze dryers for the pharmaceutical and biotech industries and has an in-depth knowledge of lyophilization technology.
Produtos e Tecnologias
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Bloco de compressão homogeneizador
As cabeças de compressão da GEA são o centro pulsante do homogeneizador, pois podem ativar o processo de homogeneização, bombeando o produto em alta pressão até que ele flua dentro da válvula de homogeneização.
Clarificador
Centrífugas clarificadoras são usadas para separar sólidos dos líquidos. A centrífuga é equipada com um jogo de pratos cônicos para a criação de uma grande área de clarificação equivalente em um volume de tambor relativamente pequeno.
Dispositivos analíticos, de controle em linha e de medição
Combinar o processo de monitoramento usando analisadores on-line, juntamente com princípios de engenharia de processo sólidos e técnicas de modelização de processo avançadas permitirá que os processos sejam ativamente controlados de modo a compensar as variações de entrada.
GEA Varipump
The pump models in the GEA Varipump line are conceived for extreme application demands and are individually optimized for your task.
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