ConsiGma®

ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines

A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.

Pharma Technology Compression

Continuous Direct Compression

ConsiGma® DC-LB Lines integrate continuous dry blending using linear blenders and tablet compression into one efficient continuous production system.

Available in 2 standard sizes, depending on the desired throughput (from 1 to 100 kg/h or 20,000 to 150,000 tablets/h to be verified by testing), the systems can be customized with a number of options to suit customer needs.

The Conductor 4.0 software ensures seamless control of the entire process and provides full reporting and track & trace.

Mainly targeted towards high-value products (low dose API), orphan drugs and new chemical entities, and particularly suited for challenging recipes that require two-stage blending or more dispersive blending, the systems can be equipped with cleaning and containment features to handle highly potent formulations.

Standard Configuration

  • Up to 6 loss-in-weight feeders with automatic top-up systems

  • 2 linear blenders

  • GEA compression system

Available Options

  • PAT tools

  • Hot swap parts for fast changeover

  • Material handling system including containment features

  • Containment upgrade

  • Coater

Main Benefits

  • Reduced risk of segregation – no material hold-ups

  • Highest possible blend homogeneity – all powder particles go through the same mixing event

  • Higher material yield

  • High flexibility from very low to very high API content

  • In process blend uniformity control – second-by-second

  • Adaption to variable throughput capacities

  • No hold-up issues

  • Wider drug load range than batch processing

  • System automatically adapts to changes in bulk density

  • Adaptable top-up sizes to ensure accurate feeding

  • Automatically adjustable dwell time

  • Flexible batch size

  • Smaller footprint

Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.

Downloads

GEA İçgörüleri

Tailored milking equipment supports cow and farmer well-being

Healthy and happy cows are the key to successful and sustainable milk production. Keeping their cows healthy, therefore, is at the heart of every dairy farmer’s effort. Many factors influence the well-being of a cow, such as...

GEA’nın bütüncül mühendislik çözümleri ile net sıfır hedefine ulaşma

Her bir sektör, karbonsuzlaştırma konusunda katı yönetmeliklere ve kanunlara uyum sağlamaya çalışırken, bir yandan da net sıfır hedeflerine ulaşma yolunda yoğun çaba sarf etmekte. Aynı zamanda, şirketler karlılıklarını artırmaya...

...Yeni gıda için masada: Gıdamızın geleceğini şekillendiriyoruz

Kahve, kakao, süt, et, balık ve yumurta - bu günlük temel gıdalar, büyük ölçüde yoğun tarıma bel bağlamaktadır. Yeni gıda teknolojilerinin yükselişiyle birlikte, artık daha sürdürülebilir alternatiflere sahibiz. GEA Sıvı, Fermantasyon...

Haberleri GEA’dan alın

GEA haber bültenine abone olarak GEA yeniliklerinden ve hikayelerinden haberdar olun.

Bizimle iletişime geçin

Size yardımcı olmak için buradayız! Sadece bir kaç detay ile sorunuza yanıt verebileceğiz.