Integrated Granulation Processing
Integrated Granulators & Dryers
GEA is uniquely qualified to provide integrated pharmaceutical process lines. Drawing on its world-class expertise and technologies, we offer an entire range of state-of-the-art process equipment that has been designed and built with system integration in mind.
Integrated by Design
A modular approach allows customers to select standard process modules to suit specific project needs: fully integrated turnkey installations can be supplied, including fluid bed process equipment combined with top- and bottom-drive high shear mixer-granulators with integrated contained materials handling, wet and dry milling facilities, product handling systems, binder and coating preparation units, filtration units and tablet compression machines.
Safety, containment, product flow and building requirements are in-built for full integration and optimum process efficiency. Our service includes design, installation assistance, commissioning and process validation, as well as training and technical support. Installation, operation qualification and documentation are done according to FDA/GAMP guidelines.
Controlling Your Process
Advanced PLC-based automation provides seamless integration of process and CIP control functions. Options include a graphical MMI operator interface, online monitoring and trending, recipe handling, batch management, barcoding and full CIM integration. Industry standard communication networks ensure full compatibility with existing control strategies and plant-wide supervisory systems.
Process Analytical Technology
The FDA’s PAT (Process Analytical Technology) initiative has enabled GEA to combine its equipment design skills and process engineering know-how to integrate online (PAT) analyzers into its systems in a way that can provide real insight into the operation of the process and help customers to achieve key product quality targets.
The goal of the PAT initiative is to ensure that pharmaceutical products are manufactured using processes that are understood and monitored so that the key quality characteristics of the products can be actively controlled.
Containment
Our distinctive specialization lies in the integration of the BUCK® containment technology into complete solutions for pharmaceutical solid dosage form facilities. With an emphasis on quality and GMP standards, we are committed to working together with our customers to deliver custom-built, first class solutions for projects of all sizes and complexity.
Safety and the Environment
For full compliance with national, local and in-house regulations, GEA offers a range of emission control options including solvent recovery systems, outlet filters and full containment plants. Equipment can be supplied to meet explosion-proof and pressure shock standards as required.
Cleaning and Maintenance
Process optimisation depends on efficient, effective cleaning. Automation of the cleaning process ensures repeatability, allows validation and minimizes downtime. In recognition of the fundamental role played in today’s advanced powder processing industry by automated clean-in-place procedures, GEA has developed a unique approach to CIP.
Concealed services: The integrated design ensures that all lines and hoses for the utilities of the plant (water, electricity, hydraulics, etc.) are concealed. This creates a safe and uncluttered working space.
CIP and WIP systems: More efficient cleaning is one of the key advantages of system integration. We provide validated cleaning with minimal downtime. GEA offers CIP-by-design (patented) features into all of its process. Every aspect of the integrated plant, from inlet to discharge, has been value-engineered for optimum cleanability. Spray system, tanks cleaners, nozzles and seals are an integral part of our equipment design. Every plant delivered by GEA has a tailor made WIP or CIP system that suits your process.
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相关产品
Fluid Bed Processing of Pharmaceuticals
GEA supplies fluid bed processors (known as fluid bed Multi-Processor in the USA) for blending, granulating, drying, pelletizing and coating for the pharmaceutical industry.
Gral High Shear Granulators
Whether the customer’s requirement is for high shear mixing or granulation, GEA has a solution for every processing challenge and can help select the technology that is most suitable for your Pharma application.
PMA High Shear Processor
PMA Bottom-drive High Shear Granulators suitable for the high speed dispersion of dry powders, aqueous or solvent granulations, effervescent production and melt pelletization for Pharmaceutical applications.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
GEA 洞察
定制挤奶设备支持奶牛和农场主的福祉
健康快乐的奶牛是成功和可持续牛奶生产的关键。因此，保持奶牛健康是每个奶农努力的核心。奶牛的健康受到许多因素影响，例如根据奶牛个体需求进行适当喂养、良好的饲养条件以及新鲜的空气、水和光照。而且，挤奶方式对奶牛的健康状况也有很大的影响。GEA 因其“优质挤奶理念”而闻名，不断致力于进一步发展，并在动物健康和牛奶质量方面取得更好的成果。
利用 GEA 的整体工程解决方案实现净零排放
各行各业都在努力实现净零排放目标，同时遵守严格的脱碳法规和立法。与此同时，公司必须平衡日益增长的质量、产品开发和工艺优化需求，此外，还必须努力提高盈利能力。应对这一挑战需要采取 GEA 提供的协作和整体方法。
在餐桌上享用…新食品：打造我们食品的未来
咖啡、可可、牛奶、肉类、鱼类和蛋类 - 这些日常主食在很大程度上依赖集约农业。随着新食品技术的兴起，我们有了更多可持续的替代品。我们采访了 GEA 液体、发酵和灌装部门的高级副总裁 Reimar Gutte 博士，探讨其中的可能性和政策。
