Continuous Processing Lines for Pharma
A Continuous process is a process where raw materials are continuously fed into a system at the same time as finished product is continuously removed at the end of the process train. The raw materials are processed in very small quantities, compared to batch processes, and in a controlled manner, which allows the operator to have consistent control over the critical process parameters and therefore the critical product quality attributes.
At GEA, we believe that continuous processing improves the quality of pharmaceutical end products: by focusing on quality during the whole product lifecycle, not just “tested in” quality; and by understanding the capability of your processes, managing sources of variability and decreasing any associated risks.
Our solution for continuous drying and particle processing plants is ConsiGma®, a 6 sigma-inspired manufacturing platform, incorporating different technologies to produce oral solid dosage forms in a continuous, cost-efficient way:
- by collecting more information during R&D phase, in a short time with less product
- by excluding risky, time- and product consuming scale-up exercises
- by introducing online measurement and closed loop control targeting real-time release (6 sigma production)
- by incorporating flexible batch size (JIT production), reducing inventory
- by reducing the energy cost per tablet, reducing environmental impact.
Products
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ConsiGma® Conductor 4.0
An indispensable part of the ConsiGma 4.0 portfolio, the Conductor 4.0 control system architecture ensures smooth operation and communication between the different elements of a pharmaceutical continuous manufacturing line
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
ConsiGma® Granulation and Compression (GC) Lines
Highly integrated solutions for continuous wet granulation, drying and tablet compression, the ConsiGma® GC lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled granulation and improved quality.
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GEA Insights
Nourrir le futur : La puissance novatrice de la lyophilisation
Pour nous, chez GEA, la réduction des déchets est importante. Nous sommes conscients qu’en exploitant la puissance de la technologie de la lyophilisation, nous pouvons transformer les denrées alimentaires en excédent en produits de valeur qui dureront longtemps, pour aider à réduire les déchets, allonger la durée de conservation et mettre en place un système agroalimentaire plus résilient pour les générations à venir.
GEA et Pulmuone rendent hommage à des générations de fabrication artisanale de naengmyeon
Lorsque le producteur de denrées alimentaires à base végétale sud-coréen Pulmuone a mis GEA au défi de moderniser ses nouilles froides traditionnelles, les « naengmyeon », les spécialistes R&D de GEA ont saisi la balle au bond. Ils ont aidé l’entreprise à développer un plat, qui est aujourd’hui une vraie réussite commerciale et dont la production consomme moins d’eau et d’électricité que les méthodes qui existaient auparavant. Le résultat est, par ailleurs, fidèle aux origines traditionnelles de ce plat et aux racines de Pulmuone, qui sont la santé, le bien-être et le développement durable.
