Liquid Dosage
Protein-based therapeutics are increasingly being developed as new chemical entities in the pharmaceutical and life science industries. Unlike small molecules, which are typically synthesized using chemical processes, most proteins need to be processed in living systems, mostly by recombinant DNA technology. The proteins can then be produced in their functional form (quaternary structure), rather than by microbial biosynthesis (bacteria/yeast), substantially reducing the downstream stages of the process.
As the demand for large-volume products increases, so does the requirement for higher capacity reactors (up to 20,000 L) to realize economies of scale. GEA has responded to the changing needs of biopharmaceutical manufacturers and developed improved technology solutions to optimize both upstream and, with increasing titers, downstream processing, in terms of time and cost efficiency.
Based on its history of innovation and process development, GEA has a thorough working knowledge of therapeutic protein production and has used this competence to design better media and feeding strategies, optimize the fermentation stage and enhance physicochemical conditions during the manufacturing process.
A leading international supplier of integrated process systems, our extensive portfolio of products, technologies and services includes standard and customized fermenters, separators and entire production lines, as well as plant for the production, storage and distribution of clean utilities. Systems for the preparation of media, fluid management, cell cultivation and purification are also part of our global scope of supply.
As a competent manufacturer of complete plant for the life science industries, GEA is a full-service provider of solutions that meet your exact requirements and specifications. From planning, development and installation to qualification and maintenance, our experienced engineers will collaborate with your project team to supply innovative and efficient process solutions for your applications.
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GEA's thorough understanding of the lyophilization process enables them to supply a comprehensive range of products and services, comprising laboratory equipment, pilot plants for research and small-scale production batches, industrial size pharmaceutical production freeze dryers.
Компрессионные головки компании GEA являются сердцем гомогенизатора, так как они запускают процесс гомогенизации, перекачивая продукт под высоким давлением, пока он не попадет в гомогенизирующий клапан.
GEA Hilge предлагает широкий ассортимент центробежных и кулачковых насосов для широкого спектра применений в производстве напитков, а также в пищевой и фармацевтической промышленности.
В течение определенного времени компания GEA задавала стандарт для гомогенизаторов высокого давления для использования в фармацевтической промышленности и секторе биотехнологий. Наше предложение включает как стендовые лабораторные установки, так и специализированные, производственные платформенные установки для целей НИОКР и производства, использ...
GEA's innovative process marks a milestone in the pretreatment of biofuels such as hydro-treated vegetable oil and sustainable aviation fuel. By eliminating the bleaching process, manufacturers benefit from significant savings potential: over 50% lower operating costs and up to 12% less CO2 emissions.
Изменение климата и растущее население планеты оказывают повышенное давление на энергоемкую пищевую промышленность, чтобы накормить больше людей и при этом не нанести вред планете. Джордж Шеперд, менеджер по глобальной технической устойчивости компании GEA, объясняет, как компания GEA использует свои инженерные ноу-хау, чтобы помочь переработчикам производить продукцию более устойчиво и при этом повысить производительность.
The world's population is growing and with it demand for milk. Dairy is an essential component of many global diets. However, its production can be resource-intensive and impact the environment. GEA’s Christian Müller, Senior Director Sustainability Farm Technologies, sheds light on how technological innovations powered by GEA make milk production more efficient and profitable.