Liquid Dosage
Hormones & Steroids
Steroids, endogenous hormones such as the sex hormones estrogen and testosterone or the hormones of the adrenal cortex, cortisol and aldosterone, play a key role in metabolic processes and have a number of pharmaceutical applications, including hormone therapy, anti-rheumatic, anti-arthritic and bodybuilding preparations.
Mainly used in the global hormone replacement therapy, currently worth about $3.6 billion, the three major segments comprise estrogen, growth and thyroid hormone, and testosterone replacement therapy. A major market driver is the increased awareness of postmenopausal hazards amongst women; others include an ageing population, innovative drug delivery systems and the pharmerging economies.
Predominantly based on cholesterol, steroid hormones are synthesized in the endocrine glands and transported to target tissue by the blood. At their site of action, they dock with highly specific cellular receptors and perform a key function in protein formation. To produce steroid hormones for pharmaceutical applications outside the body, a direct extraction procedure from special nutrient solutions is used.
Counter-Current Liquid-Liquid Extraction
In continuous direct extraction from GEA, the fermented nutrient solution is treated by liquid-liquid extraction in a counter-current process. Following precipitation, concentration, crystallization and drying of the extract, the steroid hormones are available in the form of a raw salt and can be correspondingly processed by the pharmaceutical industry. In a continuous direct extraction process, the fermented nutrient solution undergoes a counter-current liquid-liquid extraction process (also known as also known as solvent extraction or partitioning). Following precipitation, concentration, crystallization and drying, the extracted steroid hormones are available in the form of a raw salt and can be subsequently processed by the pharmaceutical industry.
Fromfacility design and layout, manufacturing process controls (including adherence to standard operating procedures) and environmental control systems (HVAC) to extraction systems, industrial hygiene solutions and fully integrated, end-to-end containment solutions, GEA has the experience and know-how to implement and optimize end-to-end production lines for steroid- and hormone-based applications.
产品与技术
显示 4 个，共 26 个
CIP/SIP 解决方案
GEA 创新的 CIP 理念可满足全方位的高标准要求。我们的专家可确保产品在每个工艺点的安全。我们的每一次升级都基于当地的情况和客户的具体要求，可为客户实现显著地成本节约。
GEA Varipump
The pump models in the GEA Varipump line are conceived for extreme application demands and are individually optimized for your task.
Hygienic pumps
GEA Hilge 提供种类繁多的离心泵和容积泵，适用于饮料、食品和制药行业的各种敏感应用。
Industrial spray dryers
Our fully customizable and highly reliable spray dryers deliver quality powders that enable you to meet your customers’ needs today and tomorrow.
Downloads
GEA 洞察
定制挤奶设备支持奶牛和农场主的福祉
健康快乐的奶牛是成功和可持续牛奶生产的关键。因此，保持奶牛健康是每个奶农努力的核心。奶牛的健康受到许多因素影响，例如根据奶牛个体需求进行适当喂养、良好的饲养条件以及新鲜的空气、水和光照。而且，挤奶方式对奶牛的健康状况也有很大的影响。GEA 因其“优质挤奶理念”而闻名，不断致力于进一步发展，并在动物健康和牛奶质量方面取得更好的成果。
利用 GEA 的整体工程解决方案实现净零排放
各行各业都在努力实现净零排放目标，同时遵守严格的脱碳法规和立法。与此同时，公司必须平衡日益增长的质量、产品开发和工艺优化需求，此外，还必须努力提高盈利能力。应对这一挑战需要采取 GEA 提供的协作和整体方法。
在餐桌上享用…新食品：打造我们食品的未来
咖啡、可可、牛奶、肉类、鱼类和蛋类 - 这些日常主食在很大程度上依赖集约农业。随着新食品技术的兴起，我们有了更多可持续的替代品。我们采访了 GEA 液体、发酵和灌装部门的高级副总裁 Reimar Gutte 博士，探讨其中的可能性和政策。
