Liquid Dosage
Antibiotics
Antibiotics, compounds or substances that combat bacterial infections and kill or slow down their growth, comprise one of the most important groups of drugs in the fight against infectious diseases. Representing around 13% of total pharmaceutical consumption, they have the highest market share of any pharmaceutical product.
In liquid-based applications, the pharmaceutical industry extracts antibiotics from fermentation broths. GEA supports this process with special decanters that facilitate the process, offering efficient direct extraction solutions that are also environmentally friendly.
The Extraction Process
Extraction essentially consists of two combined processes: mixing and separating. GEA has developed a patented decanter that combines the two process steps in a single machine to enhance the extraction of active ingredients.
This decanter allows suspensions with a high solids content to be processed, rendering them suitable for direct antibiotic extraction from the culture solution (which often has a high mycelium content). The previously essential filtration step is no longer required, which not only makes the process continuous, it also prevents the loss of valuable material that was frequently associated with filtration.
Advantages of Direct Extraction
Offering increased total yields of up to 98% compared with conventional counter-current extraction, direct extraction is also significantly more cost-effective (no filter aids are needed). The fermentation broth itself is not diluted by filter wash water, which both reduces the solvent requirement and the risk of infection. In addition, the optimized procedure also reduces wastewater pollution and the actual volume of wastewater produced.
The GEA Solution
Driven by new product innovations, high levels of R&D investment and the pharmaceutical industry’s need to ameliorate the issue of antibiotic resistance, the antibiotic market is expected to show continued growth. From R&D-scale and standalone manufacturing equipment to completely integrated process lines that maximize operational reliability, GEA supplies a complete range of equipment and solutions for the industrial-scale production of antibiotics, antibacterials and anti-infectives.
产品与技术
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CIP/SIP 解决方案
GEA 创新的 CIP 理念可满足全方位的高标准要求。我们的专家可确保产品在每个工艺点的安全。我们的每一次升级都基于当地的情况和客户的具体要求，可为客户实现显著地成本节约。
GEA Varipump
The pump models in the GEA Varipump line are conceived for extreme application demands and are individually optimized for your task.
Hygienic pumps
GEA Hilge 提供种类繁多的离心泵和容积泵，适用于饮料、食品和制药行业的各种敏感应用。
Industrial spray dryers
Our fully customizable and highly reliable spray dryers deliver quality powders that enable you to meet your customers’ needs today and tomorrow.
