ConsiGma®
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
Available in 3 standard sizes, depending on the desired throughput (from 10 to 200 kg/h or 20,000 to 400,000 tablets/h, to be verified by testing), the systems can be customized with a number of options to suit customer needs.
The Conductor 4.0 software ensures seamless control of the entire process and full reporting. Tracking of OOS and material genealogy can be integrated into the controls.
Mainly targeted towards generics, nutraceuticals, OTC production and CMOs, the systems are designed to handle easy-to-blend and high-throughput DC formulations.
Standard Configuration
- 2 to 4 loss-in-weight feeders
- 1 ribbon blender
- GEA compression system
Available Options
- Choice of feeder (GEA or qualified third-party supplier)
- Set-up of blender: continuous flow or mini-batch
- Blend uniformity measurement with Lighthouse Probe®
- Material handling system including containment features
Main Benefits
- Flexible batch size
- Small footprint
- Eliminate work in progress
- Adaptable to blending of even fragile particles such as MUPS
- Higher blend homogeneity – all powder particles go through the same mixing event
- Higher material yield
- High flexibility from very low to very high API content
- In-process blend uniformity control – second-by-second
- Adaption to variable throughput capacities
- No hold-up issues
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
Downloads
منتجات ذات صلة
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Tablet Coating (TC) Modules
The ConsiGma® TC modules are based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
ConsiGma® R&D Granulation and Drying (GD)
The ConsiGma® GD 25/80 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
رؤى GEA
معدات حلب مخصصة تدعم صحة الأبقار والمزارعين
الأبقار الصحية والسعيدة هي الأساس لإنتاج الحليب بشكل ناجح ومستدام. وبالتالي، الحفاظ على صحة الأبقار هو جوهر جهود كل مزارع الألبان. هناك العديد من العوامل التي تؤثر على صحة البقرة، مثل التغذية الملائمة وفقًا لاحتياجات البقرة الفردية،...
تحقيق صافي الانبعاثات الصفري من خلال حلول الهندسة الشاملة المقَدَّمة من GEA
تبذل الشركات المصنعة في جميع المجالات قصارى جهدها لتحقيق أهداف صافي الانبعاثات الصفري مع الالتزام باللوائح السارية والتشريعات الصارمة المتعلقة بنزع الكربون. وفي الوقت نفسه، يجب على الشركات تحقيق التوازن بين الطلب المتزايد على...
على الطاولة من أجل ... أغذية جديدة: تشكيل مستقبل أغذيتنا
القهوة، الكاكاو، الحليب، اللحوم، الأسماك والبيض - تعتمد هذه المواد الغذائية الأساسية على الزراعة الكثيفة بشكلٍ كبير. ولكن أصبحت لدينا بدائل أكثر استدامة مع ظهور تكنولوجيات الأغذية الجديدة. جلسنا مع الدكتور رايمار جوت، نائب الرئيس...
