Coating is an important unit operation used to either modify color, give protection, for taste masking or to create a modified release form in pharmaceutical production. GEA is able to offer some novel as well as all typically used coater systems for particles, powders, granules, crystals, pellets and tablets.
NexGen Press® 30 with integrated ConsiGma® coater
GEA is an established supplier of coater systems for particles, powders, granules, crystals, pellets and tablets and is able to provide equipment for many of the typically used coating technologies and assist with the selection of the process that best suits your needs.
Coating is an important unit operation that’s used extensively in the pharmaceutical industry for the application of non-functional or functional coats (aesthetic, protective or rate controlling polymer films) and for the deposition of active pharmaceutical ingredients (APIs) onto nonpareils (multi-particulate dosage forms). Applications include taste masking, color modification, physical protection and/or to create modified release forms.
Beyond efficient API layering techniques for multi-particulate systems, the pharmaceutical industry has an inherent need to accurately coat objects that are 3–30 mm in length (the most common size range for single-unit solid dosage forms) with APIs. These include tablets for oral administration and other delivery methods (human implantation, for example). Existing coating methods in this size range have coating speed and accuracy/uniformity limitations, particularly for the deposition of low dose APIs onto single unit tablet dosage forms.
Available technologies include fluid bed coating for smaller particles, such as powders, granules, seeds, crystals, pellets, and small tablets, a multipurpose processor that uses proven fluid bed technology to achieve granulation, drying and pellet coating (or tablet coating) in a single processor and a revolutionary tablet coater that accurately deposits controlled amounts of coating materials on tablets, even if they are hygroscopic or friable.
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Committed to providing flexible, modular equipment to support research and development in the pharmaceutical industry, the multipurpose AirConnect from GEA delivers a range of fluid bed processing solutions for small-scale applications.
The ConsiGma® TC modules are based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
FlexStream™ is een nieuwe multifunctionele processor die een einde maakt aan de huidige tekortkomingen van traditionele wervelbedden, met betrekking tot bijv. lineaire schaalvergroting en volledig gesloten laden en lossen voor farmaceutische toepassingen.
GEA has expanded its popular PharmaConnect® system with the introduction of PharmaConnect®-PLUS, extending the unit’s high shear granulation capacity to encompass batch sizes of up to 60 kg.
ConsiGma Coater - real-time video of coating cycle
Toen de Zuid-Koreaanse ‘plant-forward’ voedselproducent Pulmuone bij GEA aanklopte met de uitdaging om een moderne draai aan de traditionele taaie koude (naengmyeon-) noodle te geven, konden de R&D-experts van GEA de uitdaging aan. Ze hielpen met de ontwikkeling van wat nu een commerciële hit is die met minder water en elektriciteit wordt geproduceerd dan de reeds bestaande methoden. Het resultaat is ook getrouw aan de traditionele oorsprong van het gerecht, evenals de wortels van Pulmuone op het gebied van gezondheid, welzijn en duurzaamheid.
GEA’s innovatieve proces is een mijlpaal in de voorbehandeling van biobrandstoffen zoals waterstofbehandelde plantaardige olie (HVO) en duurzame vliegtuigbrandstof (SAF). Door het bleekproces te elimineren, kunnen fabrikanten profiteren van enorme besparingsmogelijkheden: ruim 50% lagere bedrijfskosten en tot 12% minder CO2-emissies.