ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines

A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.

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Continuous Direct Compression

ConsiGma® DC-LB Lines integrate continuous dry blending using linear blenders and tablet compression into one efficient continuous production system.

Available in 2 standard sizes, depending on the desired throughput (from 1 to 100 kg/h or 20,000 to 150,000 tablets/h to be verified by testing), the systems can be customized with a number of options to suit customer needs.

The Conductor 4.0 software ensures seamless control of the entire process and provides full reporting and track & trace.

Mainly targeted towards high-value products (low dose API), orphan drugs and new chemical entities, and particularly suited for challenging recipes that require two-stage blending or more dispersive blending, the systems can be equipped with cleaning and containment features to handle highly potent formulations.

Standard Configuration

Up to 6 loss-in-weight feeders with automatic top-up systems
2 linear blenders
GEA compression system

Available Options

PAT tools
Hot swap parts for fast changeover
Material handling system including containment features
Containment upgrade
Coater

Main Benefits

Reduced risk of segregation – no material hold-ups
Highest possible blend homogeneity – all powder particles go through the same mixing event
Higher material yield
High flexibility from very low to very high API content
In process blend uniformity control – second-by-second
Adaption to variable throughput capacities
No hold-up issues
Wider drug load range than batch processing
System automatically adapts to changes in bulk density
Adaptable top-up sizes to ensure accurate feeding
Automatically adjustable dwell time
Flexible batch size
Smaller footprint

Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.

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GEA 洞察

定制挤奶设备支持奶牛和农场主的福祉

健康快乐的奶牛是成功和可持续牛奶生产的关键。因此，保持奶牛健康是每个奶农努力的核心。奶牛的健康受到许多因素影响，例如根据奶牛个体需求进行适当喂养、良好的饲养条件以及新鲜的空气、水和光照。而且，挤奶方式对奶牛的健康状况也有很大的影响。GEA 因其“优质挤奶理念”而闻名，不断致力于进一步发展，并在动物健康和牛奶质量方面取得更好的成果。

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