ConsiGma®
ConsiGma® Direct Compression with Ribbon Blending (DC-RB) Lines
A cost-effective solution for continuous dry blending and tablet compression using ribbon blending, ConsiGma® DC-RB lines make the advantages of continuous manufacturing (supply chain agility, small footprint and improved quality) available for all.
Available in 3 standard sizes, depending on the desired throughput (from 10 to 200 kg/h or 20,000 to 400,000 tablets/h, to be verified by testing), the systems can be customized with a number of options to suit customer needs.
The Conductor 4.0 software ensures seamless control of the entire process and full reporting. Tracking of OOS and material genealogy can be integrated into the controls.
Mainly targeted towards generics, nutraceuticals, OTC production and CMOs, the systems are designed to handle easy-to-blend and high-throughput DC formulations.
Standard Configuration
- 2 to 4 loss-in-weight feeders
- 1 ribbon blender
- GEA compression system
Available Options
- Choice of feeder (GEA or qualified third-party supplier)
- Set-up of blender: continuous flow or mini-batch
- Blend uniformity measurement with Lighthouse Probe®
- Material handling system including containment features
Main Benefits
- Flexible batch size
- Small footprint
- Eliminate work in progress
- Adaptable to blending of even fragile particles such as MUPS
- Higher blend homogeneity – all powder particles go through the same mixing event
- Higher material yield
- High flexibility from very low to very high API content
- In-process blend uniformity control – second-by-second
- Adaption to variable throughput capacities
- No hold-up issues
Read more about how GEA and its partners are implementing this technology to lead the way toward smaller, more flexible, continuous processing technologies that are transforming the future of pharmaceutical development and manufacturing.
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相关产品
ConsiGma® Direct Compression with Linear Blending (DC-LB) Lines
A highly integrated solution for continuous linear blending and direct compression, the ConsiGma® DC-LB lines offer all the advantages of continuous manufacturing: supply chain agility, small footprint, controlled blending and compression and improved quality.
ConsiGma® Tablet Coating (TC) Modules
The ConsiGma® TC modules are based on the GEA high-performance tablet coating technology that gently and accurately deposits controlled amounts of coating materials onto tablet cores — even if they are hygroscopic or friable.
Lighthouse Probe® - online measurement
The Lighthouse Probe® can be used for real-time monitoring of chemical and pharmaceutical processes and provides in-process window cleaning at any time, recalibration during the process, full CIP (cleaning) of wash housing and seal, and a clear view inside – even in difficult conditions.
ConsiGma® R&D Granulation and Drying (GD)
The ConsiGma® GD 25/80 offers standalone continuous twin-screw granulation and drying for small-scale R&D operations. It allows users to develop the process and achieve high granule quality on a compact unit.
GEA 洞察
定制挤奶设备支持奶牛和农场主的福祉
健康快乐的奶牛是成功和可持续牛奶生产的关键。因此，保持奶牛健康是每个奶农努力的核心。奶牛的健康受到许多因素影响，例如根据奶牛个体需求进行适当喂养、良好的饲养条件以及新鲜的空气、水和光照。而且，挤奶方式对奶牛的健康状况也有很大的影响。GEA 因其“优质挤奶理念”而闻名，不断致力于进一步发展，并在动物健康和牛奶质量方面取得更好的成果。
利用 GEA 的整体工程解决方案实现净零排放
各行各业都在努力实现净零排放目标，同时遵守严格的脱碳法规和立法。与此同时，公司必须平衡日益增长的质量、产品开发和工艺优化需求，此外，还必须努力提高盈利能力。应对这一挑战需要采取 GEA 提供的协作和整体方法。
在餐桌上享用…新食品：打造我们食品的未来
咖啡、可可、牛奶、肉类、鱼类和蛋类 - 这些日常主食在很大程度上依赖集约农业。随着新食品技术的兴起，我们有了更多可持续的替代品。我们采访了 GEA 液体、发酵和灌装部门的高级副总裁 Reimar Gutte 博士，探讨其中的可能性和政策。
