Semi-Solids
Topical semi-solid dosage forms for the pharmaceutical industry can be formulated as creams, gels, ointments or pastes. As well as an active ingredient, they may also contain emulsifiers, stabilizing agents, viscosity modifiers and, in some applications, antioxidants.Gels (sometimes call jellies) can be used to administer drugs via the skin or bodily cavities, depending on the desired therapeutic effect and the site of action or administration.
Whatever it is you want to produce in your process plant, our wide range of plant modules will perform any task and meet any requirements or conditions. By using the latest components and valve technology, and the latest manufacturing concepts for vessels and skids, we ensure that you will be able to use your plant to manufacture your product in a manner that is economic, gentle and efficient.
Topical formulations present many challenges regarding bioavailability and stability. As such, controlling material parameters such as particle size and viscosity are critical. By contrast, gels are becoming increasingly important in the pharmaceutical industry as, compared with pastes and creams, it’s easier to confirm the full dissolution of the active ingredient, as well as providing superior absorption characteristics.
In the home and personal care sector, this product form can be processed into clear, shear thinning formulations for shower gels, shaving gels, toothpastes, hair care products (microemulsions), deodorants and liquid soaps. They usually comprise water or alcoholic solutions that are gelled or thickened with specific agents such as natural gums, acrylic polymers or cellulosic-type polymers.
Offering comprehensive system engineering and project management for the pharmaceutical, biotech and personal care industries, GEA’s is a market-leading provider of equipment for powder and liquid mixing and blending, intermediate storage, temperature treatment, filtration, separators, homogenization, CIP/SIP solutions and automation systems.
Our pant is designed to be free from dead-leg areas, completely drainable, suitable for CIP/SIP and sample collection, and compatible with a wide range of valves and/or piping.
Supplying consultancy, engineering, automation, process vessels, skids/units, installation, qualification and assistance with validation, our experienced process engineers will work with your team to develop innovative and efficient process technologies that meet the exact needs of your application.
Showing 4 of 20
An aseptic pigging system allows to recover cost intensive products out of product lines. Powered by compressed sterile air, the pig pushes the product out of the pipe. The remaining product film on the inside of the product line can then be removed with the CIP.
Aseptic valves face exceptionally high demands within UltraClean and Aseptic processes. You can be assured that they all provide highest quality in terms of hygienic design and sustainability.
Aseptic back-pressure valves are used to regulate a pre-defined pressure in UltraClean and Aseptic processing plants.
For liquid component production processes, GEA's efficient in-line blending systems provide the solution you need!
Other applications
Healthy and happy cows are the key to successful and sustainable milk production. Keeping their cows healthy, therefore, is at the heart of every dairy farmer’s effort. Many factors influence the well-being of a cow, such as...
Industries across the board are working hard to meet net-zero targets while navigating stringent decarbonization regulations and legislation. At the same time, companies must balance growing demands for quality, product development...
The story of the GEA centrifuge begins in 1893, when Franz Ramesohl and Franz Schmidt began production of their patented mechanical milk separator, paving the way for modern dairy processing. The innovation helped overcome a...