Liquid Dosage
Therapeutical Proteins
Protein-based therapeutics are increasingly being developed as new chemical entities in the pharmaceutical and life science industries. Unlike small molecules, which are typically synthesized using chemical processes, most proteins need to be processed in living systems, mostly by recombinant DNA technology. The proteins can then be produced in their functional form (quaternary structure), rather than by microbial biosynthesis (bacteria/yeast), substantially reducing the downstream stages of the process.
The GEA Advantage
As the demand for large-volume products increases, so does the requirement for higher capacity reactors (up to 20,000 L) to realize economies of scale. GEA has responded to the changing needs of biopharmaceutical manufacturers and developed improved technology solutions to optimize both upstream and, with increasing titers, downstream processing, in terms of time and cost efficiency.
Based on its history of innovation and process development, GEA has a thorough working knowledge of therapeutic protein production and has used this competence to design better media and feeding strategies, optimize the fermentation stage and enhance physicochemical conditions during the manufacturing process.
A leading international supplier of integrated process systems, our extensive portfolio of products, technologies and services includes standard and customized fermenters, separators and entire production lines, as well as plant for the production, storage and distribution of clean utilities. Systems for the preparation of media, fluid management, cell cultivation and purification are also part of our global scope of supply.
As a competent manufacturer of complete plant for the life science industries, GEA is a full-service provider of solutions that meet your exact requirements and specifications. From planning, development and installation to qualification and maintenance, our experienced engineers will collaborate with your project team to supply innovative and efficient process solutions for your applications.
Produits et technologies
Affichage de 4 sur 29
Bloc de compression pour homogénéisateur
Les têtes de compression de GEA constituent le cœur des homogénéisateurs, car elles activent le processus d'homogénéisation en pompant le produit à haute pression jusqu'à ce qu'il s'écoule dans la vanne d'homogénéisation.
Bol séparateur à chambre
Les centrifugeuses à chambre sont utilisées pour les liquides de polissage de l'industrie chimique et pharmaceutique, en particulier lorsque qu'il s'agit de récupérer les liquides clarifiés, mais aussi les solides, et que ces derniers doivent former des produits secs.
Clarificateur
Le séparateur centrifuge de clarification est utilisé pour séparer les solides contenus dans un liquide. Le séparateur est équipé d'une colonne de disques coniques qui créent une grande zone de clarification équivalente dans une chambre de taille relativement petite.
Dispositifs d'analyse, de régulation en ligne et de mesure
Associer la surveillance du procédé grâce à des analyseurs en ligne aux principes d'ingénierie de procédé et aux techniques avancées de modélisation du procédé permet de contrôler activement le procédé et de pouvoir compenser les variations de l'alimentation.
Downloads
GEA Insights
In for the better: Community engagement at GEA
To support community engagement, GEA offers employees one day of paid time off per year.
How a digital rotary parlor supports sustainable dairy farming
How do you lead a dairy farm into the next generation while ensuring a sustainable future and animal welfare while managing increasing complexity? This is a question almost every dairy farmer around the world must consider. The...
A strategy for the better: CEO interview on GEA's Mission 30
After reaching its Mission 26 targets two years early, GEA launches Mission 2030 strategy with focus on growth, value and making a positive impact.
